Monica Fedele

I was born in Naples, Italy, on March 23th 1969, where I graduated in Biological Sciences at the University of Naples. Subsequently, I specialized in Clinical Pathology and received my PhD in Cellular and Molecular Biology and Pathology at the Medical School of the University of Naples. Then, I was a postdoctoral investigator at the Thomas Jefferson University, Kimmel Cancer Institute, in Philadelphia (PA-USA), focusing on the development of HMGA and PATZ1 transgenic and knockout mouse models. Now I am Director of Research at the Institute of Endotypes in Oncology, Metabolism and Immunology (IEOMI) - formerly IEOS - of the CNR in Italy and my main interest is the role of chromatinic proteins in cancer. My main scientific achievements have been: 1) the isolation and characterization of the PATZ1 gene, 2) the demonstration of the oncogenic activity of the HMGA proteins, and 3) the discovery of their critical role in the development of pituitary adenomas.